Sugar is often associated with joy and happiness but this is certainly not entirely true when a person has high blood sugar level or also known as hyperglycaemia. Hyperglycaemia in the long run will develop into diabetes. Diabetes is a lifelong disease caused by inability of pancreas to produce insulin or the insulin is not utilised effectively by the body. Insulin is a hormone in the body that maintains the blood sugar level. It works by enabling the cell metabolism to use sugar or glucose from food to become energy. This energy will be used by the cell to maintain its function. Antidiabetic medication such as JANUMET 50-500 mg is among the many medications used to help patients control blood sugar level. The question now is, is JANUMET a good medicine for diabetes?
To understand if JANUMET is good, you may want to understand more about the drug itself. JANUMET contains metformin and sitagliptin. Metformin belongs to a class of drugs named as biguanide whereas sitagliptin belongs to a class of drugs named as dipeptidyl peptidase-4 (DPP-4) inhibitors. In general, biguanide works by decreasing the amount of glucose produced by the liver and improving the body response towards insulin whereas DPP-4 inhibitors work by preventing breakdown of GLP-1 and prolonging the action of GLP-1 to increase insulin production in the pancreas. Both of the ingredients can be considered to reduce the amount of sugar produced by the liver. These two active ingredients work together to help patients control blood sugar level.
JANUMET can be considered as a good medicine for diabetes as it helps patients to control blood sugar level better. JANUMET is generally prescribed to patients with type 2 diabetes. It is worth noting that antidiabetic medication is not the first treatment given by doctors when a person is diagnosed with diabetes. Antidiabetic medication is usually given as the last resort when lifestyle changes such as diet and exercise are unable to control the blood glucose level as targeted by the doctor. JANUMET is also prescribed for those with type 2 diabetes that is inadequately controlled by metformin or sitagliptin alone, thus, combination of the two types of antidiabetic drug or on top of insulin may be prescribed in such cases.
Dosage of JANUMET is typically individualised and is always based on the patient’s targeted blood sugar level or how responsive patients are towards the antidiabetic drugs. The general recommendation is 2 times a day after meals. This medicine should be taken as a whole and never be split or divided. When it is not taken as a whole, the efficacy of the drug may be compromised as the fixated dose is not fixed as intended to by the manufacturer and doctor. Patients may be receiving Janumet apart from diabetes and the dosage may be different than what it is recommended. Always ask the doctor if a patient feels unsure on why they received something differently than what is recommended.
JANUMET is an immediate-release medication. This means that when a person takes JANUMET, the drug is released in the body almost immediately and works right away. However, even if it is claimed to work immediately, the full effect of Janumet may take up to a few weeks before the high blood sugar level is lowered and ultimately improve A1C level up to 2.5%. Some patients may be able to feel improvement of symptoms within 4-5 days after taking the medicine. In order for patients to reap the full benefits of JANUMET, patients need to take it regularly. Taking it at the same time of the day can help patients to remember taking the medicine.
JANUMET, just as with other drugs, does have potential side effects. Common side effects include nausea, headache, diarrhoea and upper respiratory infection. Side effects that get worse should be informed to a healthcare provider. This medication usually does not cause hypoglycemia (low blood sugar). Hypoglycaemia is characterised by shaking, dizziness, hunger and sweating. However, hypoglycaemia may occur if a patient takes this medication with other antidiabetic medications. If hypoglycaemia does happen, patients should discuss this matter with their healthcare provider so that dosage adjustment can be considered. Since hypoglycaemia may occur with patients with diabetes especially when they take more than one antidiabetic medication, after a heavy physical activity or not eating enough calories throughout the day, it is advisable for patients to bring glucose tablets or sweet candy within hand reach all the time.
In essence, JANUMET is a good medicine for diabetes as it contains two active ingredients. This means the medicine works better than taking only one of the active ingredients. This also means it is more efficient for patients to be taking it at one go everyday at the same time of the day. There is no doubt that antidiabetic medicine helps patients to get a better control of their sugar level and improve their HbA1C level.